Bharat Book Bureau: PharmaPoint: Hepatitis C Virus - Japan Drug Forecast and Market Analysis to 2022
(M2 PressWIRE Via Acquire Media NewsEdge) Summary
"PharmaPoint: Hepatitis C Virus - Japan Drug Forecast and Market Analysis to 2022". Hepatitis C is a liver infection caused by the hepatitis C virus (HCV) that results in acute or chronic presentation. The disease is often asymptomatic, but infected patients may experience fatigue, joint pain, itchy skin or jaundice. There is no effective vaccine against HCV, so the market is driven by therapeutics. Currently, drug combinations containing pegylated interferon (e.g., Roche's Pegasys and Merck's PegIntron) and ribavirin (e.g., Roche's Copegus and Merck's Rebetol) are used to treat HCV infection. Patients infected with HCV genotype 1 can also have a protease inhibitor added to their combination therapy, such as Merck's Victrelis (boceprevir) or Vertex's Incivek (telaprevir). The entrance of next-generation HCV therapies is expected to fundamentally change the HCV treatment algorithm. GlobalData expects a dramatic shift favoring the uptake of interferon-free regimens due to their more tolerable side-effect profiles and decreased duration of therapy compared with the current standard of care.
The projected drivers of market growth in Japan include the launch of next-generation HCV regimens, increasing awareness of HCV, and a shift toward preventative care of HCV.
Merck's PegIntron (peginterferon alfa-2b) is the current market leader in Japan. The current standard of HCV therapy in Japan is a combination of interferon and ribavirin. The less-frequent dosing of peginterferon compared with standard interferon (i.e., once a week compared with three times a week) enabled peginterferon to quickly capture market share. In addition to standard interferon, PegIntron directly competes for market share with Roche's Pegasys (peginterferon alfa-2a). GlobalData's primary research revealed that peginterferon market position is further bolstered by the frequent use of interferon monotherapy in Japan.
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