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TMCNet:  Life Technologies Unveils New Bioinformatics Software

[April 16, 2013]

Life Technologies Unveils New Bioinformatics Software

Apr 16, 2013 (Close-Up Media via COMTEX) -- Life Technologies Corp. announced the launch of Vector NTI Express Designer, the latest advancement in its Vector NTI software platform, which offers researchers custom vector and genetic construct design and synthesis.

According to a release, the desktop software tool is designed for molecular biology, metabolic engineering, genetic engineering, and synthetic biology professionals who want to rationally design, assemble and order synthetic genetic "parts," optimizing genetic components for a broad range of applications.

An extension of the Vector NTI software offerings, the company said, Express Designer incorporates an integrated gene synthesis service for rapid sequence submission and order placement, effectively building a bridge from DNA sequence to gene synthesis. Customers can use the Express Designer software tools to design custom DNA parts and submit them directly to Life Technologies' GeneArt portal for synthesis.

"Molecular and synthetic biologists can now move from construct design to synthesis faster than ever before," said Nathan Wood, General Manager and Vice President of Synthetic Biology at Life Technologies. "This launch represents a true game changer in the ease, speed and accuracy with which investigators can design and order DNA customized to their needs, as well as the increased confidence they can have that constructs will perform successfully in their experiments." Vector NTI Express Designer also provides sequence optimization to fine tune expression levels of cloned genes, enables construction of multiple vectors for compatible and simultaneous function, and generates variants from template DNA parts, devices, and circuits more effectively. In addition to designing and ordering custom components, the software also contains an electronic database or "mini electronic lab notebook" that allows researchers to maintain a searchable record of genetic parts, constructs and experimental results that can be referred to and utilized to optimize constructs and circuits.

"The Vector NTI Express Designer will allow us to tackle difficult design challenges in synthetic biology," said Christopher Voigt, Ph.D., associate professor of Biological Engineering at M.I.T. "The software automates and facilitates the design process with an friendly graphical-user interface where well-characterized and annotated parts can be drag-and-dropped to create standard devices and advanced circuits." Voigt is a leader in the study of circuit design underlying the development of synthetic organisms, a process that requires constructing synthetic multi-gene pathways.

"The power of the Vector NTI Express Designer database is that it allows us to track and analyze our experimental results so that we avoid duplicating effort and focus on getting to the answer more quickly," said Steve Mayfield, Ph.D., professor in the Division of Biological Sciences at the University of California, San Diego. "We can focus more on what we want our constructs to do and less on how to make them do it." Mayfield is a pioneer in the genetic design of organisms such as algae for biofuel production.

More information and complete product details: www.lifetechnologies.com/vectornti.

((Comments on this story may be sent to newsdesk@closeupmedia.com))

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